Resource Type

Journal Article 144

Year

2024 1

2023 5

2022 18

2021 12

2020 14

2019 16

2018 7

2017 5

2016 3

2015 6

2014 7

2013 1

2012 6

2011 6

2010 6

2009 3

2008 3

2007 4

2006 4

2004 1

open ︾

Keywords

acute myeloid leukemia 8

acute promyelocytic leukemia 7

leukemia 7

acute lymphoblastic leukemia 5

Coronavirus disease 2019 3

prognosis 3

reverse osmosis 3

Acute toxicity 2

COVID-19 2

China 2

Philadelphia chromosome 2

acute-on-chronic liver failure 2

biomarker 2

homoharringtonine 2

membrane materials 2

mutation 2

pediatrics 2

polyamide 2

treatment 2

open ︾

Search scope:

排序: Display mode:

Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research

Jiong HU

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 45-52 doi: 10.1007/s11684-011-0117-y

Abstract:

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia.directly degrades the PML-RARα fusion transcript, leading to the differentiation and apoptosis of leukemiacells and the potential eradication of APL leukemia-initiating cells (LICs), thus making the diseasea potentially curable type of leukemia.

Keywords: acute promyelocytic leukemia     arsenic     all-trans retinoic acid     survival    

Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocyticleukemia

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 909-918 doi: 10.1007/s11684-021-0890-1

Abstract: In patients with acute promyelocytic leukemia (APL), intracranial hemorrhage (ICH), if not identified

Keywords: acute promyelocytic leukemia     intracranial hemorrhage     cytokines     biomarker    

Current treatment strategy of acute promyelocytic leukemia

Jianqing Mi

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 341-347 doi: 10.1007/s11684-011-0169-z

Abstract: Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML).

Keywords: acute promyelocytic leukemia     all-trans retinoic acid     arsenic trioxide    

network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic response in acutepromyelocytic leukemia

Frontiers of Medicine doi: 10.1007/s11684-023-1022-x

Abstract: The treatment of PML/RARA+ acute promyelocytic leukemia (APL) with all-trans-retinoic acid and arsenicand provides an information-rich reference data cohort for the exploratory and translational study of leukemia

Keywords: acute promyelocytic leukemia     plasma proteomics     plasma metabolomics     cross-sectional correlation network    

Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acutepromyelocytic leukemia

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 420-429 doi: 10.1007/s11684-016-0478-3

Abstract: cyclin-dependent kinase inhibitors is a target of the PML/RARα oncofusion protein in leukemogenesis of acutepromyelocytic leukemia (APL).

Keywords: CDKN2C     acute promyelocytic leukemia     cell cycle arrest     differentiation    

upregulated by PML/RARα fusion protein and promotes plasminogen-dependent fibrinolysis and matrix invasion in acutepromyelocytic leukemia

Dan Huang, Yan Yang, Jian Sun, Xiaorong Dong, Jiao Wang, Hongchen Liu, Chengquan Lu, Xueyu Chen, Jing Shao, Jinsong Yan

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 410-422 doi: 10.1007/s11684-017-0527-6

Abstract: heterotetramer (AIIt) associated with PML/RARα fusion protein causes lethal hyperfibrinolysis in acutepromyelocytic leukemia (APL), but the mechanism is unclear.To facilitate the investigation of regulatory association between ANXA2 and promyelocytic leukemia/retinoic

Keywords: annexin A2-S100A10 heterotetramer     PML/RARα fusion protein     plasmin     cell invasion     acute promyelocytic leukemia    

Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 356-362 doi: 10.1007/s11684-010-0220-5

Abstract: Acute myeloid leukemia (AML) is a very heterogeneous neoplasm of the hematopoietic stem cell.

Keywords: acute myeloid leukemia     mutations     risk stratification    

BRD4 interacts with PML/RARα in acute promyelocytic leukemia

Qun Luo, Wanglong Deng, Haiwei Wang, Huiyong Fan, Ji Zhang

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 726-734 doi: 10.1007/s11684-017-0604-x

Abstract: However, few studies have investigated whether BRD4 influenced acute promyelocytic leukemia (APL), andwhether BRD4 had interaction with promyelocytic leukemia-retinoic acid receptor α (PML/RARα) fusion

Keywords: BRD4     PML/RARα     APL     interaction    

FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 896-908 doi: 10.1007/s11684-022-0944-z

Abstract: Hence, we aimed to explore its definite role in the development of acute myeloid leukemia (AML) and emphasize

Keywords: acute myeloid leukemia     FGF13     prognosis     immune-related genes     bone marrow niches    

Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the Chinese

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 518-526 doi: 10.1007/s11684-022-0958-6

Abstract: Venous thromboembolism (VTE) is a complication in children with acute lymphoblastic leukemia (ALL).

Keywords: acute lymphoblastic leukemia     child     venous thromboembolism     epidemiology     clinical characteristic     risk    

expression pattern of mutations coordinated by target repression and promoter hypermethylation in acutemyeloid leukemia

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 627-636 doi: 10.1007/s11684-020-0815-4

Abstract: Its dysfunction, caused by either fusions or mutations, is frequently reported in acute myeloid leukemia

Keywords: RUNX1     gene mutation     acute myeloid leukemia     transcriptional repression     DNA methylation    

Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia

Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 416-420 doi: 10.1007/s11684-012-0224-4

Abstract:

Acute lymphoblastic leukemia includes T-cell acute lymphoblastic leukemia (T-ALL) and B-cell acutelymphoblastic leukemia (B-ALL).This novel subtype of T-ALL was called early T-cell precursor acute lymphoblastic leukemia (ETP-ALL).Our findings demonstrate that early T-cell precursor leukemia is a very high-risk subtype of acute lymphoblasticleukemia with poor prognosis.

Keywords: acute lymphoblastic leukemia     early T precursor     prognosis    

ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 685-698 doi: 10.1007/s11684-022-0942-1

Abstract: However, little is known about the role of ACSL5 in acute myeloid leukemia (AML).

Keywords: acute myeloid leukemia     acyl-CoA synthetase long chain family member 5     Wnt3a     palmitoylation     ABT-199    

Diagnosis-related Groups (DRGs)-based payment reform to bring benefits to patient care: A case study of leukemia

Zhi-Ruo ZHANG PhD, Jian-Qing MI MD, Zhao-Jun WEN MA, Sai-Juan CHEN MD, PhD, Zhu CHEN PhD, Long-Jun GU MD, Jing-Yan TANG MD, PhD, Shu-Hong SHEN MD, PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 8-15 doi: 10.1007/s11684-010-0018-5

Abstract: the level of reimbursement from insurance is very limited, especially for critical diseases such as leukemiaTreatments of acute promyelocytic leukemia at Rui-Jin Hospital, and childhood acute lymphoblastic leukemia

Keywords: healthcare reform     diagnosis-related groups     clinical paths     comparative effectiveness analysis     acute promyelocyticleukemia     childhood acute lymphoblastic leukemia    

comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific antibodies against B-cell acutelymphoblastic leukemia: targeted immunotherapy for acute lymphoblastic leukemia

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 139-149 doi: 10.1007/s11684-021-0835-8

Abstract: engager blinatumomab has shown remarkable efficacy in patients with relapsed/refractory B-cell precursor acutelymphoblastic leukemia.

Keywords: B-cell acute lymphoblastic leukemia     bispecific antibody     trispecific antibody     CD19     CD20    

Title Author Date Type Operation

Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research

Jiong HU

Journal Article

Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocyticleukemia

Journal Article

Current treatment strategy of acute promyelocytic leukemia

Jianqing Mi

Journal Article

network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic response in acutepromyelocytic leukemia

Journal Article

Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acutepromyelocytic leukemia

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Journal Article

upregulated by PML/RARα fusion protein and promotes plasminogen-dependent fibrinolysis and matrix invasion in acutepromyelocytic leukemia

Dan Huang, Yan Yang, Jian Sun, Xiaorong Dong, Jiao Wang, Hongchen Liu, Chengquan Lu, Xueyu Chen, Jing Shao, Jinsong Yan

Journal Article

Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Journal Article

BRD4 interacts with PML/RARα in acute promyelocytic leukemia

Qun Luo, Wanglong Deng, Haiwei Wang, Huiyong Fan, Ji Zhang

Journal Article

FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Journal Article

Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the Chinese

Journal Article

expression pattern of mutations coordinated by target repression and promoter hypermethylation in acutemyeloid leukemia

Journal Article

Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia

Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen

Journal Article

ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Journal Article

Diagnosis-related Groups (DRGs)-based payment reform to bring benefits to patient care: A case study of leukemia

Zhi-Ruo ZHANG PhD, Jian-Qing MI MD, Zhao-Jun WEN MA, Sai-Juan CHEN MD, PhD, Zhu CHEN PhD, Long-Jun GU MD, Jing-Yan TANG MD, PhD, Shu-Hong SHEN MD, PhD,

Journal Article

comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific antibodies against B-cell acutelymphoblastic leukemia: targeted immunotherapy for acute lymphoblastic leukemia

Journal Article